An fNIRS-Based Dynamic Functional Connectivity Analysis Method to Signify Functional Neurodegeneration of Parkinson’s Disease

Parkinson’s disease (PD) is a prevalent brain disorder, and PD diagnosis is crucial for treatment.Existing methods for PD diagnosis are mainly focused on behavior analysis, while the functional neurodegeneration of PD has not been well investigated.This paper proposes a method to signify functional neurodegeneration of PD with dynamic functi

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Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone

Mycolactone is a diffusible lipid toxin produced Drain Outlet Hose by Mycobacterium ulcerans, the causative agent of Buruli ulcer disease.Altough bacterially derived mycolactone has been shown to traffic from cutaneous foci of infection to the bloodstream, the mechanisms underpinning its access to systemic circulation and import by host cells remai

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